“Chronic irritable itch” is defined as a constant itchy sensation that’s difficult to treat, and is a common medical condition among dialysis patients. A study from the Florida campus of the Scripps Research Institute focused on a medication that could treat the condition without the adverse side effects normally associated with medicating the condition.

Researchers tested the compound, a combination of opioids and other chemicals, on mouse models to determine effectiveness. The drug compounds target receptors in the central nervous system that moderate pain perception and stress responses. It was found that the combination was successful in stopping the itch without sedation in the models. You can find more information about the study in the Journal of Neuropharmacology here.